Jeannie Little received her degrees from Northwestern University and The Florida State University. Her principal teachers include Jay Friedman, Frank Crisafulli, Charles Vernon, Arnold Jacobs, John Marcellus and William Cramer. Jeannie has served as principal trombonist of the Charlottesville Symphony Orchestra, the Illinois Chamber Symphony, Chicago Sinfonietta, and the Elgin Symphony orchestra. In addition, she has performed with the Detroit, Honolulu, Alabama, Chautauqua, and New Mexico Symphony Orchestras, and has toured and recorded with the Chicago Symphony under Leonard Bernstein.

Jeannie was a founding member of the highly acclaimed, award-winning trombone quartet, PRISMA, which toured extensively throughout the United States and Europe, and has been featured at International Trombone Workshops and the International Women's Brass Conference.

As a clinician, Little is active presenting recitals and master classes throughout the country, with recent performances at the International Trombone Festival, the Eastern Trombone Workshop, Oberlin Conservatory, and the Arizona Low Brass Symposium. She has also appeared as guest conductor and performer in the International Women's Trombone Choir at the International Trombone Workshops in 1992 and 1995. Having worked as the trombone professor at James Madison University, the Interlochen Arts Academy and the University of Hawaii, Jeannie is currently a free-lance artist and elementary orchestra teacher in Los Angeles, California.